TCF7L2 Antibody (1B1) Summary
| Immunogen |
TCF7L2 (AAH32656, 1 a.a. – 455 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPPNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSECFLNPCLSLPPITGEKKSAFATYKVKAAASAHPLQMEAY
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| Localization |
Nuclear
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| Specificity |
TCF7L2 – transcription factor 7-like 2 (T-cell specific, HMG-box)
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| Isotype |
IgG1 Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
TCF7L2
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| Purity |
IgG purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactivity against cell lysate and recombinant protein for WB. It has been used for RNAi Validation and ELISA.
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
IgG purified
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Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for TCF7L2 Antibody (1B1)
- HMG box transcription factor 4
- hTCF-4
- T-cell factor 4
- T-cell factor-4 variant A
- T-cell factor-4 variant B
- T-cell factor-4 variant C
- T-cell factor-4 variant D
- T-cell factor-4 variant E
- T-cell factor-4 variant H
- T-cell factor-4 variant I
- T-cell factor-4 variant J
- T-cell factor-4 variant K
- T-cell factor-4 variant L
- T-cell factor-4 variant M
- T-cell factor-4 variant X2
- T-cell-specific transcription factor 4
- TCF-4T-cell factor-4 variant F
- TCF4T-cell factor-4 variant G
- transcription factor 7-like 2 (T-cell specific, HMG-box)
- transcription factor 7-like 2
Background
The TCL7L2 gene product is a high mobility group (HMG) box-containing transcription factor implicated in blood glucose homeostasis. The study of Yi et al. (2005) [PubMed 15525634] suggested that TCL7L2 acts through regulation of proglucagon (MIM 138030) through repression of the proglucagon gene in enteroendocrine cells via the Wnt signaling pathway.[supplied by OMIM]