S-2238

Product Name :
S-2238

Description:
S-2238 is a chromogenic substrate for thrombin that is used in amidolytic assay.

CAS:
64815-81-2

Molecular Weight:
552.63

Formula:
C27H36N8O5

Chemical Name:
N-(N2-(D-phenylalanyl)-N2-(4-nitrophenyl)-L-arginyl)piperidine-2-carboxamide

Smiles :
NC(=N)NCCC[C@@H](C(=O)NC(=O)C1CCCCN1)N(C1C=CC(=CC=1)[N+]([O-])=O)C(=O)[C@H](N)CC1C=CC=CC=1

InChiKey:
NTHQWZZGIFUBPR-CTDXOEGXSA-N

InChi :
InChI=1S/C27H36N8O5/c28-21(17-18-7-2-1-3-8-18)26(38)34(19-11-13-20(14-12-19)35(39)40)23(10-6-16-32-27(29)30)25(37)33-24(36)22-9-4-5-15-31-22/h1-3,7-8,11-14,21-23,31H,4-6,9-10,15-17,28H2,(H4,29,30,32)(H,33,36,37)/t21-,22?,23+/m1/s1

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
S-2238 is a chromogenic substrate for thrombin that is used in amidolytic assay.|Product information|CAS Number: 64815-81-2|Molecular Weight: 552.63|Formula: C27H36N8O5|Synonym:|S 2238|S2238|S-2238|Related CAS Number:|160192-34-7 (hydrochloride)|62354-65-8 (dihydrochloride)|Chemical Name: N-(N2-(D-phenylalanyl)-N2-(4-nitrophenyl)-L-arginyl)piperidine-2-carboxamide|Smiles: NC(=N)NCCC[C@@H](C(=O)NC(=O)C1CCCCN1)N(C1C=CC(=CC=1)[N+]([O-])=O)C(=O)[C@H](N)CC1C=CC=CC=1|InChiKey: NTHQWZZGIFUBPR-CTDXOEGXSA-N|InChi: InChI=1S/C27H36N8O5/c28-21(17-18-7-2-1-3-8-18)26(38)34(19-11-13-20(14-12-19)35(39)40)23(10-6-16-32-27(29)30)25(37)33-24(36)22-9-4-5-15-31-22/h1-3,7-8,11-14,21-23,31H,4-6,9-10,15-17,28H2,(H4,29,30,32)(H,33,36,37)/t21-,22?,23+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Lurasidone} web|{Lurasidone} 5-HT Receptor|{Lurasidone} Biological Activity|{Lurasidone} Data Sheet|{Lurasidone} manufacturer|{Lurasidone} Epigenetics} |Shelf Life: ≥12 months if stored properly.{{Tolebrutinib} medchemexpress|{Tolebrutinib} Btk|{Tolebrutinib} Purity & Documentation|{Tolebrutinib} Formula|{Tolebrutinib} manufacturer|{Tolebrutinib} Epigenetics} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:27108903 |Drug Formulation: To be determined.|HS Tariff Code: 382200|References:|Fukuda C, Iijima K, Nakamura K. [Clinical evaluations of antithrombin III and alpha 2-plasmin inhibitor assay method with chromogenic substrates (S-2238, S-2251 (author’s transl)]. Rinsho Byori. 1981 Feb;29(2):179-82. Japanese. PubMed PMID: 6453246.Girolami A, Patrassi G, Toffanin F, Saggin L. Chromogenic substrate (S-2238) prothrombin assay in prothrombin deficiencies and abnormalities. Lack of identity with clotting assays in congenital dysprothrombinemias. Am J Clin Pathol. 1980 Jul;74(1):83-7. PubMed PMID: 7395819.van Voorthuizen H, Kluft C. Improved assay conditions for automated antithrombin III determinations with the chromogenic substrate S-2238. Thromb Haemost. 1984 Dec 29;52(3):350-3. PubMed PMID: 6531759.Goodnight SH Jr, Schaeffer JL, Sheth K. Measurement of antithrombin III in normal and pathologic states using chromogenic substrate S-2238. Comparison with immunoelectrophoretic and factor Xa inhibition assays. Am J Clin Pathol. 1980 May;73(5):639-47. PubMed PMID: 7377131.Tsuda T, Yoshimura H, Hamasaki N. Development of a new colorimetric method for protein S activity measurement. Clin Chem Lab Med. 2004 Mar;42(3):350-2. PubMed PMID: 15080571.Products are for research use only. Not for human use.|

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