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Matrix Metalloproteinase-8 (MMP-8) fluorometric drug discovery kit
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A QUANTIZYME® Assay System. The MMP-8 Fluorometric (also known as fluorimetric) Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-8 (MMP-8, neutrophil collagenase, collagenase-2) using a quenched fluorogenic peptide: OMNIMMP® fluorogenic substrate Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2. Mca fluorescence is quenched by the Dpa group until cleavage by MMPs at the Gly-Leu bond separates the two moieties. The assays are performed in a convenient 96-well microplate format.{{19171-19-8} web|{19171-19-8} Protocol|{19171-19-8} In stock|{19171-19-8} manufacturer} Also included are active enzyme, a prototypic control inhibitor (NNGH3), and a detailed instruction booklet.{{30195-30-3} MedChemExpress|{30195-30-3} Protocol|{30195-30-3} Data Sheet|{30195-30-3} supplier}
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| Alternative Name Neutrophil collagenase, Collagenase-2 | Application Fluorescent detection, HTS | Contents MMP-8 enzyme (human) (recombinant), substrate, calibration standard, inhibitor, assay buffer, 96-well white microplate.PMID:31082094 | UniProt ID P22894