October 2024

Mal-PEG24-NHS ester

pyruvate-dehydrogenase inhibitor October 31, 2024 No Comments

Product Name : Mal-PEG24-NHS esterDescription:Mal-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.CAS: 2226733-37-3Molecular Weight:1394.55Formula: C62H111N3O31Chemical Name: 2,5-dioxopyrrolidin-1-yl 1--3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72-tetracosaoxapentaheptacontan-75-oateSmiles : O=C(CCN1C(=O)C=CC1=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=OInChiKey: GRDUWUCYIIEBIS-UHFFFAOYSA-NInChi :…

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TMC310911

pyruvate-dehydrogenase inhibitor October 30, 2024 No Comments

Product Name : TMC310911Description:TMC310911 is a potent and orally active HIV type-1 (HIV-1) protease inhibitor with EC50 values ranged from 2.2 nM to 14.2 nM for wild-type HIV-1. TMC310911 has…

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Acridine Orange hydrochloride

pyruvate-dehydrogenase inhibitor October 30, 2024 No Comments

Product Name : Acridine Orange hydrochlorideDescription:Acridine Orange hydrochloride is a cell-permeable fluorescent dye that binds to nucleic acids, resulting in an altered spectral emission.CAS: 65-61-2Molecular Weight:301.81Formula: C17H20ClN3Chemical Name: N3,N3,N6,N6-tetramethylacridine-3,6-diamine hydrochlorideSmiles…

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Bromochloroacetonitrile

pyruvate-dehydrogenase inhibitor October 29, 2024 No Comments

Product Name : BromochloroacetonitrileDescription:Bromochloroacetonitrile is a by-product of the chlorine disinfection of water containing natural organic material. Bromochloroacetonitrile possesses direct acting mutagenic activity and is capable of inducing DNA strand…

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MES sodium salt

pyruvate-dehydrogenase inhibitor October 28, 2024 No Comments

Product Name : MES sodium saltDescription:MES (2-Morpholinoethanesulphonic acid) sodium salt, a zwitterionic buffer, is effective in the pH range of 5.5-7.7. MES sodium salt, as one of the Good’s buffers,…

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Apigenin-7-O-(2G-rhamnosyl)gentiobioside

pyruvate-dehydrogenase inhibitor October 27, 2024 No Comments

Product Name : Apigenin-7-O-(2G-rhamnosyl)gentiobiosideDescription:Apigenin-7-O-(2G-rhamnosyl)gentiobioside is a flavone glycosides from Lonicera gracilipes var. glandulosa.CAS: 174284-20-9Molecular Weight:740.66Formula: C33H40O19Chemical Name: 7-{oxy}methyl)-3-{oxy}oxan-2-yl]oxy}-5-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-oneSmiles : C1O(O2(O(CO3O(CO)(O)(O)3O)(O)2O)OC2=CC3OC(=CC(=O)C=3C(O)=C2)C2C=CC(O)=CC=2)(O)(O)1OInChiKey: LXOPDILLGIDKLW-KDGNLIIISA-NInChi : InChI=1S/C33H40O19/c1-11-22(38)25(41)29(45)32(47-11)52-30-27(43)24(40)20(10-46-31-28(44)26(42)23(39)19(9-34)50-31)51-33(30)48-14-6-15(36)21-16(37)8-17(49-18(21)7-14)12-2-4-13(35)5-3-12/h2-8,11,19-20,22-36,38-45H,9-10H2,1H3/t11-,19+,20+,22-,23+,24+,25+,26-,27-,28+,29+,30+,31+,32-,33+/m0/s1Purity: ≥98% (or refer to the Certificate of…

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Cixiophiopogon A

pyruvate-dehydrogenase inhibitor October 26, 2024 No Comments

Product Name : Cixiophiopogon ADescription:Cixiophiopogon A, a steroidal glycoside, obtained from the tuberous roots of Ophiopogon japonicus (Liliaceae).CAS: 288143-27-1Molecular Weight:887.02Formula: C44H70O18Chemical Name: (2S,3R,4R,5R,6S)-2-{icosan]-18′-ene-2′,8′-dioloxy]-4-{oxy}oxan-3-yl]oxy}-6-methyloxane-3,4,5-triolSmiles : C12CC(CC1=CC12CC2(C)3(O)(C21O)O1(CC(C)CO1)3C)O1O(CO)(O)(O2OC(O)(O)2O)1O1O(C)(O)(O)1OInChiKey: XEMVQWDHRXAQNR-YVEJFGEMSA-NInChi : InChI=1S/C44H70O18/c1-19-8-13-43(56-17-19)21(3)44(54)28(62-43)15-42(53)25-7-6-22-14-23(9-11-40(22,4)24(25)10-12-41(42,44)5)58-39-36(61-38-34(52)32(50)29(47)20(2)57-38)35(31(49)27(16-45)59-39)60-37-33(51)30(48)26(46)18-55-37/h6,19-21,23-39,45-54H,7-18H2,1-5H3/t19-,20+,21-,23+,24+,25-,26-,27-,28+,29+,30+,31-,32-,33-,34-,35+,36-,37+,38+,39-,40+,41+,42-,43-,44-/m1/s1Purity: ≥98% (or…

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Anhydrotetracycline hydrochloride

pyruvate-dehydrogenase inhibitor October 25, 2024 No Comments

Product Name : Anhydrotetracycline hydrochlorideDescription:Anhydrotetracycline hydrochloride, a tetracycline biosynthetic precursor, is a potent competitive broad-spectrum tetracycline destructase enzymes inhibitor. Anhydrotetracycline hydrochloride is an effector for tetracycline controlled gene expression systems…

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Propargyl-PEG1-SS-PEG1-acid

pyruvate-dehydrogenase inhibitor October 24, 2024 No Comments

Product Name : Propargyl-PEG1-SS-PEG1-acidDescription:Propargyl-PEG1-SS-PEG1-acid is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).CAS: 1807503-85-0Molecular Weight:264.36Formula: C10H16O4S2Chemical Name: 3-(2-{disulfanyl}ethoxy)propanoic acidSmiles : C#CCOCCSSCCOCCC(O)=OInChiKey: OEMFYMUYWYWVRT-UHFFFAOYSA-NInChi :…

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Mal-PEG4-C2-NH2 TFA

pyruvate-dehydrogenase inhibitor October 24, 2024 No Comments

Product Name : Mal-PEG4-C2-NH2 TFADescription:Mal-PEG4-C2-NH2 TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.CAS: 2512227-13-1Molecular Weight:430.37Formula: C16H25F3N2O8Chemical Name: 1-(14-amino-3,6,9,12-tetraoxatetradecan-1-yl)-2,5-dihydro-1H-pyrrole-2,5-dione; trifluoroacetic acidSmiles : NCCOCCOCCOCCOCCN1C(=O)C=CC1=O.OC(=O)C(F)(F)FInChiKey: VZGVXVADGJIXQP-UHFFFAOYSA-NInChi…

Mal-PEG24-NHS ester

TMC310911

Acridine Orange hydrochloride

Bromochloroacetonitrile

MES sodium salt

Apigenin-7-O-(2G-rhamnosyl)gentiobioside

Cixiophiopogon A

Anhydrotetracycline hydrochloride

Propargyl-PEG1-SS-PEG1-acid

Mal-PEG4-C2-NH2 TFA

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