Product Name :
Diketone-PEG4-Biotin
Description:
Diketone-PEG4-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
2353409-85-3
Molecular Weight:
678.84
Formula:
C33H50N4O9S
Chemical Name:
1-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}-N-[4-(3,5-dioxohexyl)phenyl]-3,6,9,12-tetraoxapentadecan-15-amide
Smiles :
CC(=O)CC(=O)CCC1C=CC(=CC=1)NC(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21
InChiKey:
CJUCDLZQRUQWCG-OLWNVYNHSA-N
InChi :
InChI=1S/C33H50N4O9S/c1-24(38)22-27(39)11-8-25-6-9-26(10-7-25)35-31(41)12-14-43-16-18-45-20-21-46-19-17-44-15-13-34-30(40)5-3-2-4-29-32-28(23-47-29)36-33(42)37-32/h6-7,9-10,28-29,32H,2-5,8,11-23H2,1H3,(H,34,40)(H,35,41)(H2,36,37,42)/t28-,29-,32-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Patritumab deruxtecan} MedChemExpress|{Patritumab deruxtecan} Antibody-Drug Conjugates (ADCs)|{Patritumab deruxtecan} Purity & Documentation|{Patritumab deruxtecan} References|{Patritumab deruxtecan} manufacturer|{Patritumab deruxtecan} Autophagy}
Shelf Life:
≥12 months if stored properly.{{Emixustat} site|{Emixustat} Biological Activity|{Emixustat} In Vivo|{Emixustat} manufacturer|{Emixustat} Epigenetics}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33147078
Additional information:
Diketone-PEG4-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 2353409-85-3|Molecular Weight: 678.84|Formula: C33H50N4O9S|Chemical Name: 1-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}-N-[4-(3,5-dioxohexyl)phenyl]-3,6,9,12-tetraoxapentadecan-15-amide|Smiles: CC(=O)CC(=O)CCC1C=CC(=CC=1)NC(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21|InChiKey: CJUCDLZQRUQWCG-OLWNVYNHSA-N|InChi: InChI=1S/C33H50N4O9S/c1-24(38)22-27(39)11-8-25-6-9-26(10-7-25)35-31(41)12-14-43-16-18-45-20-21-46-19-17-44-15-13-34-30(40)5-3-2-4-29-32-28(23-47-29)36-33(42)37-32/h6-7,9-10,28-29,32H,2-5,8,11-23H2,1H3,(H,34,40)(H,35,41)(H2,36,37,42)/t28-,29-,32-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|