Product Name :
SHP2 IN-1
Description:
SHP2 IN-1 (compound 13) is an allergic inhibitor of SHP2 (PTPN11), with an IC50 of 3 nM.
CAS:
1801764-90-8
Molecular Weight:
441.38
Formula:
C18H22Cl2N6OS
Chemical Name:
(2S,4R)-4-amino-8-{6-amino-5-[(2,3-dichloropyridin-4-yl)sulfanyl]pyrazin-2-yl}-8-azaspiro[4.5]decan-2-ol
Smiles :
NC1=NC(=CN=C1SC1=CC=NC(Cl)=C1Cl)N1CCC2(C[C@H](O)C[C@H]2N)CC1
InChiKey:
VCACXGULTWUFOL-ZYHUDNBSSA-N
InChi :
InChI=1S/C18H22Cl2N6OS/c19-14-11(1-4-23-15(14)20)28-17-16(22)25-13(9-24-17)26-5-2-18(3-6-26)8-10(27)7-12(18)21/h1,4,9-10,12,27H,2-3,5-8,21H2,(H2,22,25)/t10-,12-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
SHP2 IN-1 (compound 13) is an allergic inhibitor of SHP2 (PTPN11), with an IC50 of 3 nM.|Product information|CAS Number: 1801764-90-8|Molecular Weight: 441.38|Formula: C18H22Cl2N6OS|Chemical Name: (2S,4R)-4-amino-8-{6-amino-5-[(2,3-dichloropyridin-4-yl)sulfanyl]pyrazin-2-yl}-8-azaspiro[4.5]decan-2-ol|Smiles: NC1=NC(=CN=C1SC1=CC=NC(Cl)=C1Cl)N1CCC2(C[C@H](O)C[C@H]2N)CC1|InChiKey: VCACXGULTWUFOL-ZYHUDNBSSA-N|InChi: InChI=1S/C18H22Cl2N6OS/c19-14-11(1-4-23-15(14)20)28-17-16(22)25-13(9-24-17)26-5-2-18(3-6-26)8-10(27)7-12(18)21/h1,4,9-10,12,27H,2-3,5-8,21H2,(H2,22,25)/t10-,12-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Dinutuximab} MedChemExpress|{Dinutuximab} Biological Activity|{Dinutuximab} References|{Dinutuximab} custom synthesis|{Dinutuximab} Autophagy} |Shelf Life: ≥12 months if stored properly.{{Pitavastatin} MedChemExpress|{Pitavastatin} Autophagy|{Pitavastatin} Biological Activity|{Pitavastatin} In Vitro|{Pitavastatin} custom synthesis|{Pitavastatin} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24633055 |Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|