Transglutaminase 2/TGM2 Antibody (1A6) Summary
| Immunogen |
TGM2 (AAH03551, 1 a.a. – 120 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSVVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE
|
| Specificity |
TGM2 – transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (1A6)
|
| Isotype |
IgG2a Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
TGM2
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Transglutaminase 2/TGM2 Antibody (1A6)
- C polypeptide
- EC 2.3.2.13
- G-ALPHA-h
- protein-glutamine gamma-glutamyltransferase 2
- protein-glutamine-gamma-glutamyltransferase
- TG(C)
- TG2
- TGase C
- TGase H
- TGase-2
- TGase-H
- TGC
- TGCGNAH
- TGM2
- Tissue transglutaminase
- transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
- Transglutaminase 2
- Transglutaminase C
- Transglutaminase H
- transglutaminase-2
- tTG
Background
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.