Onucleotide therapy of breast cancer cells enhances their sensitivity to anticancer drugs. Int J Oncol 22: 87581. Elbashir, SM, Harborth, J, Lendeckel, W, Yalcin, A, Weber, K and Tuschl, T (2001). Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411: 49498. Pecot, CV, Calin, GA, Coleman, RL, Lopez-Berestein, G and Sood, AK (2011). RNA interference in the clinic: challenges and future directions. Nat Rev Cancer 11: 597. Petros, RA and DeSimone, JM (2010). Approaches within the style of nanoparticles for therapeutic applications. Nat Rev Drug Discov 9: 61527. Filion MC, Phillips NC (1998) Significant limitations within the use of cationic liposomes for DNA delivery. Int J Pharm 162: 15970. Bertrand, JR, Pottier, M, Vekris, A, Opolon, P, Maksimenko, A and Malvy, C (2002). Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo. Biochem Biophys Res Commun 296: 1000004. Klionsky, DJ and Emr, SD (2000). Autophagy as a regulated pathway of cellular degradation. Science 290: 1717721. Dalby, KN, Tekedereli, I, Lopez-Berestein, G and Ozpolat, B (2010). Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic methods in cancer. Autophagy 6: 32229. Akar, U, Chaves-Reyez, A, Barria, M, Tari, A, Sanguino, A, Kondo, Y et al. (2008). Silencing of Bcl-2 expression by tiny interfering RNA induces autophagic cell death in MCF-7 breast cancer cells. Autophagy four: 66979. Ozpolat, B, Akar, U, Mehta, K and Lopez-Berestein, G (2007). PKC delta and tissue transglutaminase are novel inhibitors of autophagy in pancreatic cancer cells. Autophagy 3: 48083. Shen, HM and Codogno, P (2011). Autophagic cell death: Loch Ness monster or endangered species Autophagy 7: 45765. Trisciuoglio, D, Gabellini, C, Desideri, M, Ziparo, E, Zupi, G and Del Bufalo, D (2010). Bcl2 regulates HIF-1alpha protein stabilization in hypoxic melanoma cells by way of the molecular chaperone HSP90. PLoS One five: e11772. Pattingre, S, Tassa, A, Qu, X, Garuti, R, Liang, XH, Mizushima, N et al. (2005). Bcl-2 antiapoptotic CD40 Activator Purity & Documentation proteins inhibit Beclin 1-dependent autophagy. Cell 122: 92739. Oh, S, Xiaofei, E, Ni, D, Pirooz, SD, Lee, JY, Lee, D et al. (2011). Downregulation of autophagy by Bcl-2 promotes MCF7 breast cancer cell growth independent of its inhibition of apoptosis. Cell Death Differ 18: 45264. Akar, U, Ozpolat, B, Mehta, K, Lopez-Berestein, G, Zhang, D, Ueno, NT et al. (2010). Targeting p70S6K prevented lung metastasis within a breast cancer xenograft model. Mol Cancer Ther 9: 1180187. Anai, S, Dopamine Receptor Modulator site Goodison, S, Shiverick, K, Hirao, Y, Brown, BD and Rosser, CJ (2007). Knockdown of Bcl-2 by antisense oligodeoxynucleotides induces radiosensitization and inhibition of angiogenesis in human PC-3 prostate tumor xenografts. Mol Cancer Ther 6: 10111. Iervolino, A, Trisciuoglio, D, Ribatti, D, Candiloro, A, Biroccio, A, Zupi, G et al. (2002). Bcl2 overexpression in human melanoma cells increases angiogenesis via VEGF mRNA stabilization and HIF-1-mediated transcriptional activity. FASEB J 16: 1453455. Li, X and Fan, Z (2010). The epidermal development aspect receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1alpha and Bcl-2 and activating the beclin 1/hVps34 complicated. Cancer Res 70: 5942952. Ricca, A, Biroccio, A, Del Bufalo, D, Mackay, AR, Santoni, A and Cippitelli, M (2000). bcl-2 over-expression enhances NF-kappaB activity and induces mmp-9 transcription in human MCF7(ADR) breast-cancer cells. Int J.
Related Posts
Ed specificity. Such applications involve ChIPseq from restricted biological material (eg
Ed specificity. Such applications involve ChIPseq from restricted biological material (eg, forensic, ancient, or biopsy samples) or exactly where the study is limited to known enrichment web sites, hence the presence of false peaks is indifferent (eg, comparing the enrichment levels quantitatively in samples of cancer individuals, employing only selected, verified enrichment internet sites more […]
Endogenous Nampt is downregulated in response to I/R, and cardiac-distinct overexpression of Nampt guards the coronary heart
Speedy reperfusion provides gasoline for ATP production, such as glucose and fatty acidOTSSP167 hydrochlorideMELK inhibitor biological activitys, supplies oxygen, and washes out noxious substances derived from necrotic cells, but the rapid restoration of extracellular pH and the oxygen supply final results in additional Ca2+ overload and manufacturing of reactive oxygen species (ROS), causing reperfusion damage […]
D R.K., information curation K.G., R.K. as well as a.D R.K., data curation K.G., R.K.
D R.K., information curation K.G., R.K. as well as a.D R.K., data curation K.G., R.K. along with a.R.-K.; conceptualization, E.S.-Z. and also a.R.-K., funding acquisition, A.R.-K. and E.S.-Z. All authors contributed to the writing and editing in the manuscript. All authors have read and agreed to the published version with the manuscript. Funding: This investigation […]