Rabbit anti-DAPK1 Polyclonal Antibody

pyruvate-dehydrogenase inhibitor

Product Name :
Rabbit anti-DAPK1 Polyclonal Antibody

Synonym :
DAPK; ROCO3

Host :
Rabbit

Species Reactivity:
Human, Mouse, Rat

Specificity :

Predicted Reactivity:

Applications :
WB 1:500 – 1:2000IHC 1:50 – 1:100

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1141-1430 of human DAPK1 (NP_004929.2).

Concentration :

Purification :
Affinity purification

Clonality:

Storage Temp.:
Store at -20 ℃Avoid freeze / that cycles

Research areas :

Background :
Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants.

UniProt :
P53355

Additional information:
Product Details FAQ Citations(0) Video Pictures Documents |Overview |Synonym DAPK; ROCO3 |Host Rabbit |Species Reactivity Human, Mouse, Rat |Applications WB 1:500 – 1:2000IHC 1:50 – 1:100 |Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1141-1430 of human DAPK1 (NP_004929.2). |Positive control Mouse lung,Mouse kidney |Properties |Purification Affinity purification |Isotype IgG |Storage Temp. Store at -20 ℃Avoid freeze / that cycles |Storage Buffer Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |Target |Background Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants. |Cellular localization Cytoplasm,cytoskeleton,cytoskeleton |UniProt P53355 |Tips:This product is for research use only. Not for use in diagnostic prodcedures.

Rabbit anti-DAPK1 Polyclonal Antibody

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
64221-86-9 site 2004677-13-6 custom synthesis PMID:30725797 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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