Product Name :
Ac-Ile-Glu-Thr-Asp-pNA
Synonym :
Chemical Name :
CAS NO.:
219138-21-3
Molecular formula :
C27H38N6O12
Molecular Weight:
638.62 g/mol
Classification :
MedChemExpress Products > Research Chemicals > Ac-Ile-Glu-Thr-Asp-pNA
Description:
Ac-Ile-Glu-Thr-Asp-PNA is a synthetic peptide that mimics the amino acid sequence of a region in the protein p67phox, which is a component of the mitochondrial membrane. Ac-Ile-Glu-Thr-Asp-PNA induces apoptosis by activating caspases and inhibiting ATP production. In vitro studies have shown this peptide to be active against hl60 cells, an inflammatory bowel disease cell line, as well as carcinoma cell lines derived from squamous cell carcinoma and carcinoma of the cervix. Ac-Ile-Glu-Thr-Asp-PNA also inhibits inflammatory cytokines such as IL1β, TNFα and IL6, which are associated with chronic inflammation.
Purity :
>98%
Specifications :
1 mg
Price.:
72
Price unit :
$
Inventory :
In stock
Related websites: https://www.medchemexpress.com
83-46-5 site 142-83-6 Biological Activity PMID:28613723 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com