Name :
GP1BA (Human) Recombinant Protein
Biological Activity :
Human GP1BA (P07359, His17-Leu531) partial recombinant protein with His tag at C-Terminus expressed in HEK293 cells.Recombinant Human Protein,Recombinant Human Proteins,Human Recombinant Protein,Human Recombinant Proteins,HuPro
Tag :
Result of bioactivity analysis
Protein Accession No. :
P07359
Protein Accession No.URL :
https://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=2811
Amino Acid Sequence :
His17-Leu531
Molecular Weight :
57.6
Storage and Stability :
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.Aliquot to avoid repeated freezing and thawing.
Host :
Human
Interspecies Antigen Sequence :
Preparation Method :
Mammalian cell (HEK293) expression system
Purification :
Quality Control Testing :
SEC-HPLC and Tris-Bis PAGE SEC-HPLC The purity of Human CD42b is greater than 95% as determined by SEC-HPLC. Tris-Bis PAGE Human CD42b on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Storage Buffer :
Lyophilized from sterile distilled Water is > 100 ug/mL
Applications :
Enzyme-linked Immunoabsorbent Assay， Immobilized Human CD42b, His Tag at 0.5 ug/mL (100 uL/well) on the plate. Dose response curve for Anti-CD42b Antibody, hFc Tag with the EC50 of 4.0 ng/mL determined by ELISA. Functional Study， SDS-PAGE，
Gene Name :
GP1BA
Gene Description :
glycoprotein Ib (platelet), alpha polypeptide
Gene Summary :
Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq
Other Designations :
platelet glycoprotein Ib alpha polypeptide|platelet membrane glycoprotein 1b-alpha subunit
MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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