TXNRD2 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human TrxR2. The exact sequence is proprietary.
|
| Localization |
Mitochondrion
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
TXNRD2
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
56 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Expected cross reactivity based on sequence homology: Mouse (80%), Rat (80%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for TXNRD2 Antibody
- EC 1.8.1
- EC 1.8.1.9
- KIAA1652
- Selenoprotein Z
- SelZ
- Thioredoxin Reductase 2
- thioredoxin reductase 3
- thioredoxin reductase beta
- Thioredoxin reductase TR3
- TR
- TR3
- TR-beta
- TRXR2
- TRXR2thioredoxin reductase 2, mitochondrial
- TXNRD2
Background
Thioredoxin reductase (TR) is a dimeric NADPH-dependent FAD containing enzyme that catalyzes the reduction of the active site disulfide of thioredoxin and other substrates. TR is a member of a family of pyridine nucleotide-disulfide oxidoreductases and is a key enzyme in the regulation of the intracellular redox environment. Three thioredoxin reductase genes have been found that encode selenocysteine containing proteins. This gene partially overlaps the COMT gene on chromosome 22. [provided by RefSeq]