SNRPB Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human SNRPB. The exact sequence is proprietary.
|
| Localization |
Nucleus
|
| Predicted Species |
Mouse (100%), Rat (100%), Primate (96%), Monkey (100%), Chicken (96%), Bovine (99%). Backed by our 100% Guarantee.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
SNRPB
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Theoretical MW |
25 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Rhesus Monkey (100%), Chimpanzee (96%), Xenopus laevis (81%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.75 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for SNRPB Antibody
- CODB polypeptide of Sm protein
- Sm protein B/B
- small nuclear ribonucleoprotein polypeptides B and B
- small nuclear ribonucleoprotein polypeptides B and B1
- small nuclear ribonucleoprotein-associated proteins B and B
- SmB/B
- Sm-B/Bsm-B/Sm-B
- SmB/SmB
- snRNP-Bsmall nuclear ribonucleoprotein polypeptide B
- SNRPB1
Background
The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B) have been found for this gene.