Product: Ethynodiol (diacetate)
SIN3B Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human SIN3B. The exact sequence is proprietary.
|
| Localization |
Nucleus
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| Isotype |
IgG
|
| Clonality |
Polyclonal
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| Host |
Rabbit
|
| Gene |
SIN3B
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.57 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for SIN3B Antibody
- Histone deacetylase complex subunit Sin3b
- KIAA0700paired amphipathic helix protein Sin3b
- SIN3 homolog B, transcription regulator (yeast)
- SIN3 homolog B, transcriptional regulator (yeast)
- SIN3 homolog B, transcriptional regulator
- Transcriptional corepressor Sin3b
Background
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.