SEC22B Antibody Summary
| Immunogen |
A synthetic peptide as a part of human, rat, mouse, hamster, orangutan, chicken Vesicle-trafficking protein SEC22b conjugated to an immunogenic carrier protein was used as the immunogen.
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| Specificity |
SEC22B.
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| Clonality |
Polyclonal
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| Host |
Sheep
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| Gene |
SEC22B
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| Purity |
IgG purified
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Applications/Dilutions
| Dilutions |
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
PBS
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| Preservative |
No Preservative
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| Concentration |
LYOPH
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| Purity |
IgG purified
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| Reconstitution Instructions |
Reconstitute with 0.5 ml sterilized water. Add glycerol (1:1) for additional stability.
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Alternate Names for SEC22B Antibody
- ERS24
- ERS-24sec22b
- SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
- SEC22 vesicle trafficking protein homolog B (S. cerevisiae)
- SEC22 vesicle trafficking protein-like 1 (S. cerevisiae)
- SEC22 vesicle trafficking protein-like 1
- SEC22 vesicle-trafficking protein homolog B
- SEC22 vesicle-trafficking protein-like 1
- SEC22, vesicle trafficking protein (S. cerevisiae)-like 1
- SEC22L1ER-Golgi SNARE of 24 kDa
- vesicle-trafficking protein SEC22b
Background
The protein encoded by this gene is a member of the SEC22 family of vesicle trafficking proteins. It seems to complex with SNARE and it is thought to play a role in the ER-Golgi protein trafficking. This protein has strong similarity to Mus musculus and Cricetulus griseus proteins. There is evidence for use of multiple polyadenylation sites for the transcript. FUNCTION: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER. SUBUNIT: Component of two distinct SNARE complexes consisting of STX5, GOSR2/BOS1, BET1 and SEC22B or STX18, USE1L, BNIP1/SEC20L and SEC22B. YKT6 can probably replace SEC22B in either complex. SUBCELLULAR LOCATION: Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type IV membrane protein. Golgi apparatus membrane; Single-pass type IV membrane protein. Melanosome. Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV.