RASGRP3 Antibody Summary
| Immunogen |
RASGRP3 (NP_733772.1, 1 a.a. ~ 690 a.a) full-length human protein.MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYRNATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDISSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYVIHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNTLMAVVGGLSHSSISR
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| Specificity |
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
|
| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
RASGRP3
|
| Purity |
Protein A purified
|
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This antibody is reactive against mammalian transfected lysate in western blot. May also be used for ELISA.
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Reactivity Notes
Human, Mouse
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
|
| Purity |
Protein A purified
|
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for RASGRP3 Antibody
- Calcium and DAG-regulated guanine nucleotide exchange factor III
- GRP3KIAA0846ras guanyl-releasing protein 3
- Guanine nucleotide exchange factor for Rap1
- RAS guanyl releasing protein 3 (calcium and DAG-regulated)
Background
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM]