PRDC/GREM2 Antibody [Alexa Fluor® 488] Summary
| Immunogen |
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GREM2. The exact sequence is proprietary.
|
| Localization |
Secreted
|
| Specificity |
Antibody reactive against peptide, detects immunogen. Further validation in progress.
|
| Predicted Species |
Mouse (100%), Rat (100%), Primate (100%). Backed by our 100% Guarantee.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
GREM2
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Theoretical MW |
19 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Expected cross reactivity based on sequence homology: Rhesus Monkey (100%).
Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark.
|
| Buffer |
PBS
|
| Preservative |
0.05% Sodium Azide
|
| Concentration |
0.97 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for PRDC/GREM2 Antibody [Alexa Fluor® 488]
- CKTSF1B2
- CKTSF1B2FLJ21195
- Cysteine knot superfamily 1, BMP antagonist 2
- DAN domain family member 3
- DAND3
- DAND3Prdc
- GREM2
- gremlin 2
- gremlin 2, cysteine knot superfamily, homolog
- gremlin-2
- PRDC
- PRDCgremlin 2, cysteine knot superfamily, homolog (Xenopus laevis)
- Protein related to DAN and cerberus
Background
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq]