Product: BRL-15572 (dihydrochloride)
PCK2 Antibody Summary
| Immunogen |
Peptide with sequence KPWKPGDKEPCAH corresponding to internal region according to NP_004554.2.
|
| Specificity |
This antibody is expected to recognise isoform 1 (NP_004554) only, no cross-reactivity with PCK1.
|
| Clonality |
Polyclonal
|
| Host |
Goat
|
| Gene |
PCK2
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
||||
| Application Notes |
WB: Approx. 75 kDa band observed in human liver lysates is reported in scientific literature (PMID: 23466304.
|
||||
| Positive Control |
|
||||
| Publications |
|
Reactivity Notes
Predicted cross-reactivity based on sequence identity: Canine, Bovine, Porcine and Mouse
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
|
| Preservative |
0.02% Sodium Azide
|
| Concentration |
0.5 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for PCK2 Antibody
- EC 4.1.1.32
- PE
- PEPCK
- PEPCK2PEP carboxykinase
- PEPCK-M
- phosphoenolpyruvate carboxykinase [GTP], mitochondrial
- phosphoenolpyruvate carboxykinase 2 (mitochondrial)
- Phosphoenolpyruvate carboxylase
- phosphopyruvate carboxylase
Background
This gene encodes a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function, although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described.