Neuronal Pentraxin 2 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human NP2. The exact sequence is proprietary.
|
| Localization |
Secreted
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| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
NPTX2
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
47 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Expected cross reactivity based on sequence homology: Zebrafish (81%), Xenopus tropicalis (88%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.25 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Neuronal Pentraxin 2 Antibody
- Apexin
- NARP
- neuronal activity-regulated pentaxin
- Neuronal Pentraxin 2
- neuronal pentraxin IIapexin
- neuronal pentraxin-2
- NP2
- NP-II
- NPTX2
Background
This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq]