MBP Antibody (BDI221) Summary
| Immunogen |
Purified human myelin basic protein.
|
| Marker |
Oligodendrocyte Marker, Myelin Marker
|
| Specificity |
Recognizes residues 130-136 in human myelin basic protein (21.5kD and 18.5kD molecular forms).
|
| Isotype |
IgG2b
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
MBP
|
| Purity |
Protein G purified
|
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|
Applications/Dilutions
| Dilutions |
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Reactivity Notes
Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Concentration |
1 mg/ml
|
| Purity |
Protein G purified
|
Alternate Names for MBP Antibody (BDI221)
- Hmbpr
- MBP
- MGC99675
- mld
- Myelin A1 protein
- myelin basic protein
- Myelin membrane encephalitogenic protein
- shi
Background
Myelin Basic Protein (MBP) functions in the nervous system in myelination and is expressed in oligodendrocytes following differentiation. There are numerous isoforms generated by differential splicing events and post-translational modifications that have specialized functions. These functions include participation in signaling pathways prior to myelination, myelination or the re-myelination process following neural injury.