LITAF Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human LITAF. The exact sequence is proprietary.
|
| Localization |
Lysosome membrane, Peripheral membrane protein, Cytoplasmic side
|
| Predicted Species |
Monkey (96%). Backed by our 100% Guarantee.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
LITAF
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
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|
Applications/Dilutions
| Dilutions |
|
| Theoretical MW |
17 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Rhesus Monkey (96%), Mouse (85%), Rat (86%), Bovine (86%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for LITAF Antibody
- CMT1C
- FLJ38636
- lipopolysaccharide-induced TNF factor
- lipopolysaccharide-induced TNF-alpha factor
- lipopolysaccharide-induced tumor necrosis factor-alpha factor
- LITAF
- LPS-induced TNF-alpha factor
- MGC116698
- MGC116700
- MGC125275
- MGC125276
- p53-induced gene 7 protein
- PIG7
- PIG7MGC116701
- SIMPLE
- SIMPLEMGC125274
- Small integral membrane protein of lysosome/late endosome
- TP53I7
- tumor protein p53 inducible protein 7
Background
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Pagets disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]