LDB3 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human LDB3. The exact sequence is proprietary.
|
| Localization |
Cytoplasm; perinuclear region; Cell projection; pseudopodium; cytoskeleton; myofibril; sarcomere; Z-disk
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
LDB3
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
31 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for LDB3 Antibody
- CMD1C
- CYPHER
- KIAA01613
- KIAA0613FLJ35865
- LDB3Z1
- LDB3Z4
- LIM domain binding 3
- LIM domain-binding protein 3
- ORACLE
- PDLIM6
- PDZ and LIM domain 6
- Protein cypher
- ZASPLVNC3
- Z-band alternatively spliced PDZ-motif protein
Background
This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1 and 2) have C-terminal LIM domains. [provided by RefSeq]