L3MBTL1 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human L3MBTL. The exact sequence is proprietary.
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| Localization |
Nucleus
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| Isotype |
IgG
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| Clonality |
Polyclonal
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| Host |
Rabbit
|
| Gene |
L3MBTL1
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
84 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Expected cross reactivity based on sequence homology: Moue (88%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
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| Preservative |
0.01% Thimerosal
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| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for L3MBTL1 Antibody
- dJ138B7.3
- FLJ41181
- H-l(3)mbt protein
- H-L(3)MBT
- KIAA0681L3MBTLDKFZp586P1522
- l(3)mbt (Drosophila)-like
- L(3)mbt protein homolog
- l(3)mbt-like (Drosophila)
- l(3)mbt-like 1 (Drosophila)
- L(3)mbt-like
- L3MBT
- lethal (3) malignant brain tumor l(3)
- lethal(3)malignant brain tumor-like protein
Background
This gene encodes the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. This gene product is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. Alternatively spliced transcript variants encoding different isoforms have been identified.