HIV-1 p24 Antibody Summary
| Immunogen |
Purified native p24, from strain IIIB.
|
| Specificity |
Recognizes the HIV1 viral capsid p24 protein encoded by the gag gene along with p6, p7 and p17 which provide structural elements of the virus.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Goat
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
|
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
No buffer
|
| Preservative |
0.09% Sodium Azide
|
| Concentration |
4.0 mg/ml
|
| Purity |
IgG purified
|
Alternate Names for HIV-1 p24 Antibody
- Capsid protein p24
- Human immunodeficiency virus 1
- Human immunodeficiency virus type 1 p24
Background
HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. Capsid protein p24 probably forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex.