FOXE1 Antibody Summary
| Immunogen |
Peptide with sequence C-AYPGGIDRFVSAM corresponding to C-Terminus according to NP_004464.2.
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| Localization |
Nuclear
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| Clonality |
Polyclonal
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| Host |
Goat
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| Gene |
FOXE1
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
WB: Preliminary experiments gave an approx. 70 kDa band in human thymus and thyroid gland lysates after 0.3 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 38.1 kDa band according to NP_004464.2. The 70 kDa band was successfully blocked by incubation with the immunizing peptide. IHC-P: Human thyroid gland shows nuclear staining in thyrocytes.
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
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| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
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| Preservative |
0.02% Sodium Azide
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| Concentration |
0.5 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for FOXE1 Antibody
- FKHL15HFKL5
- forkhead box E1 (thyroid transcription factor 2)
- forkhead box E2
- Forkhead box protein E2
- forkhead, drosophila, homolog-like 15
- Forkhead-related protein FKHL15
- HFKH4Thyroid transcription factor 2
- TITF2HNF-3/fork head-like protein 5
- TTF2forkhead box protein E1
- TTF-2FOXE2
Background
This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. This gene functions as a thyroid transcription factor which likely plays a crucial role in thyroid morphogenesis. Mutations in this gene are associated with congenital hypothyroidism and cleft palate with thyroid dysgenesis. The map localization of this gene suggests it may also be a candidate gene for squamous cell epithelioma and hereditary sensory neuropathy type I.