Product: Fasudil (Hydrochloride)
DEDD Antibody Summary
| Immunogen |
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human DEDD. The exact sequence is proprietary.
|
| Localization |
Cytoplasm, Nucleus, nucleolus
|
| Predicted Species |
Mouse (100%), Rat (100%), Bovine (100%), Xenopus (100%), Rhesus Macaque (100%). Backed by our 100% Guarantee.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
DEDD
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
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|
Applications/Dilutions
| Dilutions |
|
| Theoretical MW |
37 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.42 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for DEDD Antibody
- CASP8IP1
- death effector domain containing
- death effector domain-containing protein
- Death effector domain-containing testicular molecule
- death effector domain-containing
- DEDD1
- DEDPRO1
- DEFTKE05
- FLDED1
- FLDED-1
Background
This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.