Complement Component C9 Antibody (X197) Summary
| Immunogen |
Human C9 is used for the immunogen. The exact sequence is proprietary.
|
| Specificity |
This product is useful for detecting Component C9. This is also specific for inhibition of C9 binding to C5b-8.
|
| Isotype |
IgG1
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
C9
|
| Purity |
Protein A or G purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
|
| Application Notes |
The antibody can be used for immuno assays, flow cytometry and Western blotting.
|
|
| Publications |
|
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
0.2 um filtered solution in PBS and 0.1% BSA
|
| Preservative |
No Preservative
|
| Concentration |
0.1 mg/ml
|
| Purity |
Protein A or G purified
|
Alternate Names for Complement Component C9 Antibody (X197)
- complement component 9
- Complement Component C9
Background
Human C9 is a soluble glycoprotein of 61 kD. It is the last component in the assembly of the membrane attack complex (MAC). When the complement is activated on target membranes, multiple copies of C9 bind to the C5b-8 complex and assemble the barrel-shaped pore which causes cell lysis. The conformation of C9 changes from globular to a tubular form. The binding of C9 to C5b-8 plays a key role in the function of C9.