CDCP1 Antibody Summary
| Immunogen |
Peptide with sequence C-PLLNTQEPMEPAE corresponding to C-Terminus according to NP_073753.3.
|
| Specificity |
This antibody is expected to recognize isoform 1 (NP_073753.3) only.
|
| Clonality |
Polyclonal
|
| Host |
Goat
|
| Gene |
CDCP1
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
||
| Application Notes |
IP successful usage with A549 cells. WB: Approx. 90 kDa band observed in human colon lysates (calculated MW of 92.3 kDa band according to NP_073753.3). An additional band of unknown identity was also consistently observed at 200 kDa. This band was successfully blocked by incubation with the immunizing peptide. IHC successful usage for human endometrium.
|
||
| Positive Control |
|
||
| Publications |
|
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
|
| Preservative |
0.02% Sodium Azide
|
| Concentration |
0.5 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for CDCP1 Antibody
- CD318 antigen
- CD318
- CDCP1
- CUB domain containing protein 1
- CUB domain-containing protein 1
- Membrane glycoprotein gp140
- SIMA135
- SIMA135TRASK
- Subtractive immunization M plus HEp3-associated 135 kDa protein
- Transmembrane and associated with src kinases
Background
The protein encoded by this gene is a transmembrane protein containing three extracellular CUB domains. This protein is found to be overexpressed in colon and lung cancers. Its expression level is correlated with the metastatic ability of carcinoma cells. This protein is located on the cell surface. It has been shown to be tyrosine phosphorylated in a cancer cell line. Alternatively spliced transcript variants encoding distinct isoforms have been reported.