Anillin Antibody Summary
| Immunogen |
Peptide with sequence WQPDACYKPIGKP corresponding to C-Terminus according to NP_061155.2.
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| Clonality |
Polyclonal
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| Host |
Goat
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| Gene |
ANLN
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
WB: Preliminary experiments gave an approx. 75 kDa band in mouse brain lysates after 0.3 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 124 kDa band according to NP_061155.2. The 75 kDa band was successfully blocked by incubation with the immunizing peptide. IHC-P: Human kidney shows staining of nuclei in some cells of renal tubules.
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| Publications |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Mouse, Bovine.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
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| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
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| Preservative |
0.02% Sodium Azide
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| Concentration |
0.5 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for Anillin Antibody
- actin-binding protein anillin
- anillin (Drosophila Scraps homolog), actin binding protein
- ANILLIN
- anillin, actin binding protein (scraps homolog, Drosophila)
- anillin, actin binding protein
- DKFZp779A055
- Drosophila Scraps homolog
- scra
- Scraps
Background
Anillin is an actin-binding protein that can bind septins and is a component of the cytokinetic ring. Anillin is expressed ubiquitously but with variable levels of expression, being highest in the central nervous system. Anillin is overexpressed in diverse common human tumors, but not simply as a consequence of being a proliferation marker. Anillin may have potential as a novel biomarker.